GrippeBresilV1, Main, Exploration, bibRecord, 000317

The characteristics, clinical manifestations and outcomes of pandemic influenza A (H1N1) 2009 in the elderly.

Identifieur interne : 000317 ( Main/Exploration ); précédent : 000316; suivant : 000318

The characteristics, clinical manifestations and outcomes of pandemic influenza A (H1N1) 2009 in the elderly.

Auteurs : Luana Lenzi ; Astrid Wiens ; Roberto Pontarolo

Source :

Revista da Sociedade Brasileira de Medicina Tropical [ 1678-9849 ]

RBID : pubmed:23740069

Descripteurs français

KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Brésil (épidémiologie), Enfant, Enfant d'âge préscolaire, Facteurs de l'âge, Facteurs de risque, Facteurs socioéconomiques, Femelle, Grippe humaine (mortalité), Grippe humaine (virologie), Humains, Jeune adulte, Mâle, Pandémies, Pronostic, Répartition par sexe, Répartition par âge, Sous-type H1N1 du virus de la grippe A, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
MESH :
- mortalité : Grippe humaine.
- virologie : Grippe humaine.
- épidémiologie : Brésil.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Facteurs de l'âge, Facteurs de risque, Facteurs socioéconomiques, Femelle, Humains, Jeune adulte, Mâle, Pandémies, Pronostic, Répartition par sexe, Répartition par âge, Sous-type H1N1 du virus de la grippe A, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
Wicri :
- geographic : Brésil.

English descriptors

KwdEn :
- Adolescent, Adult, Age Distribution, Age Factors, Aged, Aged, 80 and over, Brazil (epidemiology), Child, Child, Preschool, Female, Humans, Influenza A Virus, H1N1 Subtype, Influenza, Human (mortality), Influenza, Human (virology), Male, Middle Aged, Pandemics, Prognosis, Retrospective Studies, Risk Factors, Sex Distribution, Socioeconomic Factors, Young Adult.
MESH :
- geographic , epidemiology : Brazil.
- mortality : Influenza, Human.
- virology : Influenza, Human.
- Adolescent, Adult, Age Distribution, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Influenza A Virus, H1N1 Subtype, Male, Middle Aged, Pandemics, Prognosis, Retrospective Studies, Risk Factors, Sex Distribution, Socioeconomic Factors, Young Adult.

Abstract

INTRODUCTION

The objective of this study was to evaluate the 2009 Pandemic Influenza A (H1N1) in the elderly and identify the clinical characteristics, mortality and prognostic factors of the infection in these patients.

METHODS

This was an observational, retrospective study. Data were collected from the National Notifiable Diseases (SINAN), from the Brazilian Ministry of Health. Only patients 60 years old or more that had laboratory confirmed infections were included. The socio-demographic and clinical variables and outcomes were evaluated to compare mortality rates in the presence or absence of these factors.

RESULTS

We included 93 patients in the study, 16.1% of whom died. The symptoms of cough and dyspnea, the use of the antiviral oseltamivir, influenza vaccine and comorbidities influenced the outcomes of cure or death. Chest radiography can aid in diagnosis.

CONCLUSIONS

Although relatively few elderly people were infected, this population presented high lethality that can be justified by the sum of clinical, physical and immunological factors in this population. Treatment with oseltamivir and vaccination against seasonal influenza have significantly reduced rates of hospitalization and mortality.

DOI: 10.1590/0037-8682-0024-2012
PubMed: 23740069

Affiliations:

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Le document en format XML

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<author><name sortKey="Lenzi, Luana" sort="Lenzi, Luana" uniqKey="Lenzi L" first="Luana" last="Lenzi">Luana Lenzi</name>
<affiliation><nlm:affiliation>Departamento de Farmácia, Setor de Ciências da Saúde, Universidade Federal do Paraná, Curitiba, PR.</nlm:affiliation>
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<author><name sortKey="Wiens, Astrid" sort="Wiens, Astrid" uniqKey="Wiens A" first="Astrid" last="Wiens">Astrid Wiens</name>
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<term>Sous-type H1N1 du virus de la grippe A</term>
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<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Influenza, Human</term>
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<term>Age Distribution</term>
<term>Age Factors</term>
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<term>Retrospective Studies</term>
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<term>Socioeconomic Factors</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Facteurs de l'âge</term>
<term>Facteurs de risque</term>
<term>Facteurs socioéconomiques</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
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<front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b>
</p>
<p>The objective of this study was to evaluate the 2009 Pandemic Influenza A (H1N1) in the elderly and identify the clinical characteristics, mortality and prognostic factors of the infection in these patients.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>This was an observational, retrospective study. Data were collected from the National Notifiable Diseases (SINAN), from the Brazilian Ministry of Health. Only patients 60 years old or more that had laboratory confirmed infections were included. The socio-demographic and clinical variables and outcomes were evaluated to compare mortality rates in the presence or absence of these factors.</p>
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<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>We included 93 patients in the study, 16.1% of whom died. The symptoms of cough and dyspnea, the use of the antiviral oseltamivir, influenza vaccine and comorbidities influenced the outcomes of cure or death. Chest radiography can aid in diagnosis.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Although relatively few elderly people were infected, this population presented high lethality that can be justified by the sum of clinical, physical and immunological factors in this population. Treatment with oseltamivir and vaccination against seasonal influenza have significantly reduced rates of hospitalization and mortality.</p>
</div>
</front>
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<AbstractText Label="METHODS" NlmCategory="METHODS">This was an observational, retrospective study. Data were collected from the National Notifiable Diseases (SINAN), from the Brazilian Ministry of Health. Only patients 60 years old or more that had laboratory confirmed infections were included. The socio-demographic and clinical variables and outcomes were evaluated to compare mortality rates in the presence or absence of these factors.</AbstractText>
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<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Although relatively few elderly people were infected, this population presented high lethality that can be justified by the sum of clinical, physical and immunological factors in this population. Treatment with oseltamivir and vaccination against seasonal influenza have significantly reduced rates of hospitalization and mortality.</AbstractText>
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The characteristics, clinical manifestations and outcomes of pandemic influenza A (H1N1) 2009 in the elderly.

The characteristics, clinical manifestations and outcomes of pandemic influenza A (H1N1) 2009 in the elderly.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki